Europe and Canada set more controls on workplace chemo

'Contamination is everywhere,' an expert says.


In the U.S., there's a lot of discussion about the difficulties of requiring hospitals and clinics to prove they are not contaminating their workers with toxic drugs.

But some other countries are already doing that.

In Holland, health care workers can choose to be monitored for exposure and work areas must be tested for contamination. Germany, Austria and Belgium also have aggressive safety programs regulating chemo agents. The United Kingdom and France impose strict regulation on veterinary practices handling chemo. In Canada, British Columbian hospitals do monthly safety inspections and a major union there is preparing to track nurses' health histories to link exposures to disease.

"Contamination is everywhere, even at the best organized facilities," said Paul Sessink, a chemist and toxicologist who has performed monitoring in about 300 hospitals around the world. European countries are moving to make worker safety regulations stronger, he said, while the U.S. appears almost exclusively focused on patient safety.

In British Columbia, the death of nurse Sally Giles in 1992 resulted in a set of extensive regulations governing everything from the mixing of chemo, to how it is delivered, and disposed of, said Pam Piddocke, health and safety officer for the British Columbia Nurses Union, which fought for and won the regulations. Giles was an emergency room nurse who routinely mixed and delivered chemo to patients. She died less than a year after being diagnosed in her 40s with cancer of the bile duct that she, and the union that represented her in a coroner's inquest into her death, believed was linked to her exposure.

Regulations that emerged from that case require monthly "preventive inspections" to determine that workers are following guidelines and equipment is working properly, Piddocke said.

In the U.S., however, neither environmental monitoring, nor exposure tracking is mandated. And neither is routinely taking place.

Yet U.S. studies have shown if it were done, it would likely show that most workplaces where chemo is being handled have some degree of contamination.

A new study by U.S. Centers for Disease Control and Prevention, the largest of its kind to date, has found continued evidence of contamination and exposure at three major health care institutions, according to Tom Connor, a research biologist with the National Institute for Occupational Safety and Health, and one of the principal authors of the study. Once surfaces are exposed to the drugs, they can remain contaminated for months. The study found pharmacies were more often contaminated than oncology nursing stations. One of the chemo drugs showed up in the urine of two pharmacists.

The study looked at 70 exposed workers at three hospitals, including the University of Maryland, the University of North Carolina and the University of Texas, MD Anderson. Results showed that voluntary guidelines in place since 2004 are not enough to protect workers, Connor said.

The federal Occupational Safety and Health Administration is charged with protecting workers but has no specific standard for protecting workers from exposure to toxic drugs in the health care industry. The agency has issued fewer and fewer regulations since the 1990s, said Janice Camp, a senior lecturer in the Occupational and Environmental Health Sciences Department at the University of Washington.

"The health care industry is notoriously bad for being compliant," she said. "You hear the same sort of arguments: 'Oh, it's so expensive, it's too hard, the workers won't do it. It's too hard to put ventilation in pharmacies because buildings were never designed for that,' " she said. "It's the same stuff we heard from heavy industry years ago."

U.S. Sen. Patty Murray, chair of the Employment and Workplace Safety Subcommittee, said worker safety law hasn't been updated since it was passed in 1970s, hindering the agency's ability to keep up with new hazards in the workplace..

"In fact, far from modernizing OSHA, a slew of restrictions, requirements, and administrative burdens, not to mention funding limitations, have been placed on OSHA over the past 40 years," she said.

The few standards that have emerged in recent decades have resulted because a rare cancer or disease was linked to a specific group of workers and a single source of exposures. That's how the standards for asbestos, which is linked to mesothelioma, and silica, linked to silicosis, were born. Strong labor advocacy or catastrophic situations have also pushed standards forward in the past.

Washington state, which has its own OSHA plan administered by the Department of Labor & Industries, does not do many inspections of health care workplaces, said John Furman, occupational nurse consultant for L&I.

However, in 2006, the agency did investigate a safety complaint brought by an employee of an outpatient oncology clinic in Centralia and issued citations that were disputed in court, records obtained by InvestigateWest indicate. The clinic corrected venting in a chemo mixing area and was fined for not having gowns available that protected against liquid aerosols and splashes. The inspections also included a co-owned clinic in Aberdeen. That investigation was precipitated by a worker complaint, not a routine inspection, Furman said.

Safety advocates, however, point out that many workers remain unaware of their potential exposures and question whether all dangerous situations are being brought to the attention of regulatory agencies.


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