The Detroit Lions knew nothing about success in Washington. Through 21 trips to the nation’s capital, they owned an 0-fer.
The Lions (2-1) ended a 21-game road losing streak against the Redskins, the second longest in NFL history. Detroit’s last win away from home in the series came in 1935 against the Boston Redskins, two years before the franchise’s move to Washington.
Lions 27, Redskins 20
Robert Griffin III and the defending NFC East champion Redskins fell to 0-3. Griffin completed 32 of 50 passes for 326 yards and had his fourth interception of the season, one shy of his 2012 total. The Redskins scored an offensive touchdown for the first time this season.
But they couldn’t do what every previous Washington team had done against Detroit.
Titans 20, Chargers 17
At Nashville, Locker ended the slide by completing seven passes to six receivers for 94 yards on the winning drive. He finished with 299 yards passing and ran for 68 yards. The Titans (2-1) outgained San Diego 452-277 yards, with Nate Washington catching eight passes for 131 yards. Chris Johnson ran 19 times for 90 yards.
San Diego (1-2) led most of the game despite having four starters out because of injuries and losing a fifth to an injured foot in the first half.
Colts 27, 49ers 7
At San Francisco, Andrew Luck beat college coach Jim Harbaugh. Trent Richardson scored a 1-yard touchdown on his first carry in his Colts debut after being acquired on Wednesday from the Browns. He was drafted two spots behind Luck at No. 3 last year.
Dolphins 27, Falcons 23
Ryan Tannehill’s 1-yard touchdown pass to rookie Dion Sims with 38 seconds left lifted the host Dolphins (3-0). The score capped a 13-play, 75-yard drive after Atlanta’s Matt Bryant missed a 35-yard field-goal attempt with 4:46 left. Jimmy Wilson intercepted Matt Ryan to seal the victory.
Miami fell behind 10-0 and 20-10 and trailed much of the game. The injury-plagued Falcons, who were one play from the Super Bowl last season, fell to 1-2. Atlanta lost despite advantages of 24-16 in first downs, 377-285 in yards and 5-0 in sacks.
Bengals 34, Packers 30
At Cincinnati, Terence Newman returned a fumble 58 yards for a touchdown with 3:47 left in a game of wild momentum swings set up by nonstop turnovers.
Each team gave it away four times. Each team returned a fumble for a touchdown; M.D. Jennings ran one back for Green Bay (1-2).
Ravens 30, Texans 9
At Baltimore, Daryl Smith had a 37-yard interception return for a TD, Tandon Doss took a punt 82 yards for another score, and the Ravens (2-1) won despite playing without Ray Rice for the first time since 2008. The three-time Pro Bowl running back was replaced by Bernard Pierce, who ran for 65 yards and a touchdown.
Saints 31, Cardinals 7
At New Orleans, Drew Brees passed for three scores and ran for another. He had two TD strikes to tight end Jimmy Graham and the other to Robert Meachem.
Brees was intercepted once by New Orleans native and former LSU star Tyrann Mathieu.
Browns 31, Vikings 27
At Minneapolis, tight end Jordan Cameron caught three touchdown passes, including the go-ahead grab with 51 seconds left. Third-stringer Brian Hoyer threw for three scores for the Browns (1-2), the latest team to torch Minnesota’s depleted secondary. He overcame three interceptions to throw for 321 yards, going 30 for 54.
Patriots 23, Bucs 3
Tom Brady threw two touchdown passes to Kenbrell Thompkins to lead host New England (3-0), which has yielded only 34 points this season. The Patriots held Doug Martin, who rushed for 144 yards a week earlier, to 88 yards on 20 carries.
Thompkins, an undrafted free agent, scored on plays of 16 and 5 yards.
Josh Freeman threw an interception to former Bucs cornerback Aqib Talib as the Bucs fell to 0-3.
Bears 40, Steelers 23
At Pittsburgh, Chicago’s defense forced five turnovers and scored twice. Major Wright returned an interception 38 yards for a touchdown in the second quarter, and Julius Peppers picked up Ben Roethlisberger’s fumble and raced 42 yards for a score in the fourth quarter for the Bears (3-0).
Panthers 38, Giants 0
At Charlotte, Cam Newton threw three touchdown passes and ran for another, and Carolina sacked Eli Manning seven times. It was as Tom Coughlin’s worst defeat as coach of the Giants (0-3), and the largest margin of victory for Carolina (1-2).
Cowboys 31, Rams 7
DeMarco Murray ran for 175 yards and a touchdown two years after torching St. Louis with a franchise record as a rookie, and Tony Romo threw for three scores. Murray had his first 100-yard game in more than a year.
Jets 27, Bills 20
Geno Smith threw two touchdown passes, including a go-ahead 69-yarder to Santonio Holmes in the fourth quarter in a sloppy game.
The Jets (2-1) overcame a team-record 20 penalties for 168 yards.